Helperby has announced a collaboration with Dr. Pamela Yeh and her team at the Department of Ecology and Evolutionary Biology, University of California, Los Angeles (UCLA).
Dr Yeh recently published on the phenomenon of emergent synergy of combining two or more existing antibiotics and their efficacy against pathogenic Escherichia coli1(E-coli).
It was previously held that the risks of combining antibiotic drugs often outweighed the benefit because of adverse interactions. But Dr Yeh’s team found the direct opposite, and reported that as more drugs were combined, an elevated frequency of synergy was observed1.
“In my opinion Dr Yeh’s team’s recent observations could be the most important breakthrough in the fight against antibiotic resistance,” said Professor Coates, founder and Chief Scientific Officer, Helperby.
Helperby and Dr Yeh’s team will work closely to explore the commercial opportunity of additional, new, combination therapies. The collaboration will include the sharing of data, expertise and research methodology.
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Helperby Therapeutics announces study results active against the WHO Critical Priority Carbapenem resistant bacterial pathogens